Automated description from the Alliance of Genome Resources (Release 4.0)
Enables 3'-5' DNA helicase activity. Involved in G-quadruplex DNA unwinding; negative regulation of mitotic recombination; and replication fork processing. Acts upstream of or within several processes, including DNA metabolic process; negative regulation of thymocyte apoptotic process; and positive regulation of double-strand break repair via homologous recombination. Located in chromosome; cytoplasm; and nucleus. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system gland; and mammary gland. Used to study Bloom syndrome. Human ortholog(s) of this gene implicated in Bloom syndrome. Orthologous to human BLM (BLM RecQ like helicase).