Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables glucose 6-phosphate:inorganic phosphate antiporter activity. Involved in gluconeogenesis. Acts upstream of or within several processes, including cholesterol homeostasis; glucose-6-phosphate transport; and hemopoiesis. Is active in endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; genitourinary system; liver; nervous system; and spleen. Used to study glycogen storage disease Ia. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type II; glycogen storage disease Ib; and glycogen storage disease Ic. Orthologous to human SLC37A4 (solute carrier family 37 member 4).