Automated description from the Alliance of Genome Resources
Exhibits D-erythro-sphingosine kinase activity; acetyltransferase activity; and sphinganine kinase activity. Involved in several processes, including negative regulation of ceramide biosynthetic process; regulation of vesicle-mediated transport; and sphingolipid mediated signaling pathway. Localizes to the endocytic vesicle; nucleus; and presynapse. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human SPHK1 (sphingosine kinase 1).