Automated description from the Alliance of Genome Resources
Exhibits tumor necrosis factor-activated receptor activity. Involved in several processes, including apoptotic signaling pathway; regulation of cytokine production involved in immune response; and semi-lunar valve development. Localizes to the membrane raft. Human ortholog(s) of this gene implicated in several diseases, including Legionnaires' disease; acne; bone disease (multiple); glomerulonephritis (multiple); and lung disease (multiple). Orthologous to human TNFRSF1B (TNF receptor superfamily member 1B).