Automated description from the Alliance of Genome Resources (Release 3.1.1)
A structural constituent of synapse. Involved in several processes, including adult behavior; cerebellar Purkinje cell layer morphogenesis; and synapse organization. Localizes to several cellular components, including glutamatergic synapse; parallel fiber to Purkinje cell synapse; and postsynaptic spectrin-associated cytoskeleton. Is expressed in neural tube lateral wall and ventral grey horn. Used to study spinocerebellar ataxia type 5. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 14 and spinocerebellar ataxia type 5. Orthologous to human SPTBN2 (spectrin beta, non-erythrocytic 2).