Automated description from the Alliance of Genome Resources (Release 5.2.0)
Enables calcium ion binding activity. Involved in sarcomere organization. Acts upstream of or within endoplasmic reticulum organization; regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion; and response to heat. Located in mitochondrial matrix and sarcoplasmic reticulum lumen. Is expressed in several structures, including diaphragm; heart; lung; musculature; and myotome. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human CASQ1 (calsequestrin 1).