Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits calcium ion binding activity. Involved in several processes, including regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion; response to heat; and sarcomere organization. Localizes to mitochondrial matrix and sarcoplasmic reticulum lumen. Predicted to colocalize with Golgi apparatus. Is expressed in several structures, including diaphragm; heart; lung; myotome; and skeletal muscle. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human CASQ1 (calsequestrin 1).