Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables 7-dehydrocholesterol reductase activity. Acts upstream of or within several processes, including blood vessel development; lung epithelial cell differentiation; and sterol biosynthetic process. Predicted to be located in endoplasmic reticulum and nuclear outer membrane. Is expressed in adrenal gland; genitourinary system; and neural retina. Used to study Smith-Lemli-Opitz syndrome. Human ortholog(s) of this gene implicated in Behcet's disease and Smith-Lemli-Opitz syndrome. Orthologous to human DHCR7 (7-dehydrocholesterol reductase).