Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits 7-dehydrocholesterol reductase activity. Involved in several processes, including blood vessel development; lung development; and sterol biosynthetic process. Predicted to localize to several cellular components, including endoplasmic reticulum; integral component of endoplasmic reticulum membrane; and nuclear outer membrane. Is expressed in adrenal gland; genitourinary system; and neural retina. Used to study Smith-Lemli-Opitz syndrome. Human ortholog(s) of this gene implicated in Smith-Lemli-Opitz syndrome. Orthologous to human DHCR7 (7-dehydrocholesterol reductase).