Automated description from the Alliance of Genome Resources (Release 7.0.0)
Involved in regulation of cilium beat frequency and sperm axoneme assembly. Acts upstream of or within several processes, including brain development; epithelial cilium movement involved in extracellular fluid movement; and motile cilium assembly. Located in 9+2 motile cilium; axoneme; and extracellular region. Is expressed in lateral ventricle choroid plexus and metencephalon part of 4th ventricle choroid plexus. Used to study normal pressure hydrocephalus and spermatogenic failure 19. Human ortholog(s) of this gene implicated in normal pressure hydrocephalus and spermatogenic failure 19. Orthologous to human CFAP43 (cilia and flagella associated protein 43).