Automated description from the Alliance of Genome Resources
Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and protein dimerization activity. Involved in embryonic cranial skeleton morphogenesis and negative regulation of transcription by RNA polymerase II. Localizes to the nucleus. Colocalizes with the Tle3-Aes complex. Is expressed in several structures, including branchial arch; ear; embryo mesenchyme; genitourinary system; and limb. Orthologous to human TBX15 (T-box transcription factor 15).