Automated description from the Alliance of Genome Resources
Exhibits endopeptidase activity. Involved in negative regulation of apoptotic signaling pathway; proteolysis; and regulation of autophagy of mitochondrion. Localizes to the mitochondrial inner membrane. Used to study Leigh disease. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; coronary artery disease; hyperinsulinism; myopia; and type 2 diabetes mellitus. Orthologous to human PARL (presenilin associated rhomboid like).