Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables N-acylsphingosine amidohydrolase activity. Involved in cellular response to tumor necrosis factor; regulation of programmed necrotic cell death; and sphingolipid metabolic process. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and respiratory system. Used to study Farber lipogranulomatosis. Human ortholog(s) of this gene implicated in Farber lipogranulomatosis; sphingolipidosis; and spinal muscular atrophy with progressive myoclonic epilepsy. Orthologous to human ASAH1 (N-acylsphingosine amidohydrolase 1).