Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables 3',5'-cyclic-AMP phosphodiesterase activity. Involved in cellular response to epidermal growth factor stimulus and positive regulation of ERK1 and ERK2 cascade. Predicted to be active in cytosol; nucleus; and perinuclear region of cytoplasm. Is expressed in several structures, including genitourinary system; gut gland; integumental system; nervous system; and skeleton. Orthologous to human PDE8A (phosphodiesterase 8A).