Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits several functions, including RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; chromatin binding activity; and thyroid hormone receptor coactivator activity. Involved in several processes, including cellular response to Thyroglobulin triiodothyronine; locomotor rhythm; and regulation of gene expression. Localizes to cytoplasm and nucleus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; hemolymphoid system; and sensory organ. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human NCOA2 (nuclear receptor coactivator 2).