Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits several functions, including N-acyltransferase activity; nucleic acid binding activity; and transcription factor binding activity. Involved in several processes, including animal organ development; protein acylation; and regulation of transcription, DNA-templated. Localizes to histone acetyltransferase complex and transcription regulator complex. Is expressed in several structures, including epithelium; heart; lung; nervous system; and skin. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in Rubinstein-Taybi syndrome; colorectal cancer; and congestive heart failure. Orthologous to human EP300 (E1A binding protein p300).