Automated description from the Alliance of Genome Resources
Exhibits identical protein binding activity. Involved in calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules and establishment of skin barrier. Localizes to several cellular components, including the apical plasma membrane; bicellular tight junction; and lateral plasma membrane. Human ortholog(s) of this gene implicated in Crohn's disease and atopic dermatitis. Orthologous to human CLDN1 (claudin 1).