Automated description from the Alliance of Genome Resources
Predicted to have heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Involved in angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure; positive regulation of estrogen secretion; and renal tubular secretion. Predicted to localize to the cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in hypertension; myocardial infarction; pulmonary hypertension; renal fibrosis; and renal hypertension. Is expressed in liver and metanephros. Orthologous to human CYP2J2 (cytochrome P450 family 2 subfamily J member 2).