Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to be involved in protein targeting to membrane; protein targeting to vacuole; and ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to act upstream of or within protein transport. Predicted to be located in centrosome; cytosol; and nucleoplasm. Predicted to be part of ESCRT I complex. Is expressed in several structures, including branchial arch; facial prominence; heart; limb bud; and neural fold. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 53. Orthologous to human VPS37A (VPS37A subunit of ESCRT-I).