Automated description from the Alliance of Genome Resources
Exhibits DNA (cytosine-5-)-methyltransferase activity; DNA binding activity; and chromatin binding activity. Involved in several processes, including DNA metabolic process; hypermethylation of CpG island; and negative regulation of transcription, DNA-templated. Localizes to the chromosome and cytoplasm. Human ortholog(s) of this gene implicated in acute myeloid leukemia; myelodysplastic syndrome; precursor T-lymphoblastic lymphoma/leukemia; precursor lymphoblastic lymphoma/leukemia; and stomach cancer. Orthologous to human DNMT3A (DNA methyltransferase 3 alpha).