Automated description from the Alliance of Genome Resources (Release 5.1.1)
Enables endodeoxyribonuclease activity; magnesium ion binding activity; and protein homodimerization activity. Involved in negative regulation of TOR signaling and positive regulation of autophagy. Acts upstream of or within several processes, including apoptotic DNA fragmentation; in utero embryonic development; and response to tumor necrosis factor. Located in mitochondrion. Is expressed in several structures, including central nervous system; gut; liver; male reproductive gland or organ; and respiratory system. Orthologous to human ENDOG (endonuclease G).