Automated description from the Alliance of Genome Resources (Release 3.2)
Predicted to have chromatin binding activity and thiol-dependent ubiquitin-specific protease activity. Involved in macrophage homeostasis; regulation of cytokine production involved in inflammatory response; and response to inorganic substance. Predicted to localize to PR-DUB complex; cytosol; and nucleoplasm. Is expressed in gonad; liver; and mammary gland. Used to study myelodysplastic syndrome. Human ortholog(s) of this gene implicated in basal cell carcinoma. Orthologous to human BAP1 (BRCA1 associated protein 1).