Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables aspartic-type endopeptidase inhibitor activity. Involved in several processes, including diet induced thermogenesis; establishment of protein localization; and regulation of signal transduction. Located in extracellular space; membrane; and nucleus. Is expressed in several structures, including genitourinary system; gut; hemolymphoid system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human SORL1 (sortilin related receptor 1).