Automated description from the Alliance of Genome Resources (Release 3.0)
Predicted to have ADP-ribosylation factor binding activity; amyloid-beta binding activity; and low-density lipoprotein particle binding activity. Involved in several processes, including diet induced thermogenesis; negative regulation of protein metabolic process; and regulation of signal transduction. Localizes to nuclear envelope lumen. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is expressed in several structures, including alimentary system; brain; ganglia; metanephros; and sensory organ. Orthologous to human SORL1 (sortilin related receptor 1).