Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits sequence-specific DNA binding activity. Involved in several processes, including animal organ development; positive regulation of cell development; and regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and heart. Used to study Leri-Weill dyschondrosteosis. Human ortholog(s) of this gene implicated in lung cancer. Orthologous to human SHOX2 (short stature homeobox 2).