Automated description from the Alliance of Genome Resources
Exhibits sequence-specific DNA binding activity. Involved in several processes, including animal organ development; positive regulation of cell development; and regulation of transcription by RNA polymerase II. Predicted to localize to the nucleus. Used to study Leri-Weill dyschondrosteosis. Human ortholog(s) of this gene implicated in lung cancer. Is expressed in several structures, including central nervous system; embryo mesenchyme; genitourinary system; heart; and sensory organ. Orthologous to human SHOX2 (short stature homeobox 2).