Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. Predicted to be involved in inositol phosphate catabolic process; phosphatidylinositol dephosphorylation; and synaptic vesicle endocytosis. Predicted to act upstream of or within lipid metabolic process. Predicted to be located in axon terminus; cytoplasmic microtubule; and ruffle membrane. Predicted to be active in perinuclear region of cytoplasm and presynapse. Is expressed in several structures, including alimentary system; genitourinary system; nose; spleen; and submandibular gland primordium. Orthologous to human SYNJ2 (synaptojanin 2).