Automated description from the Alliance of Genome Resources
Predicted to have DNA topoisomerase type I (single strand cut, ATP-independent) activity and single-stranded DNA binding activity. Predicted to be involved in DNA topological change; chromosome separation; and mitochondrial DNA metabolic process. Predicted to localize to the PML body. Human ortholog(s) of this gene implicated in chronic progressive external ophthalmoplegia. Is expressed in brain; female associated reproductive structure; and ureter. Orthologous to human TOP3A (DNA topoisomerase III alpha).