Gene Ontology Classifications
Summary from NCBI RefSeq This gene encodes an enzyme that proteolytically activates the pancreatic proenzyme trypsinogen, converting it into trypsin. The encoded protein is cleaved into two chains that form a heterodimer linked by a disulfide bond. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]
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Gene Ontology Evidence Code Abbreviations:
Experimental:
EXP Inferred from experiment
HMP Inferred from high throughput mutant phenotype
HGI Inferred from high throughput genetic interaction
HDA Inferred from high throughput direct assay
HEP Inferred from high throughput expression pattern
IDA Inferred from direct assay
IEP Inferred from expression pattern
IGI Inferred from genetic interaction
IMP Inferred from mutant phenotype
IPI Inferred from physical interaction
Homology:
IAS Inferred from ancestral sequence
IBA Inferred from biological aspect of ancestor
IBD Inferred from biological aspect of descendant
IKR Inferred from key residues
IMR Inferred from missing residues
IRD Inferred from rapid divergence
ISA Inferred from sequence alignment
ISM Inferred from sequence model
ISO Inferred from sequence orthology
ISS Inferred from sequence or structural similarity
Automated:
IEA Inferred from electronic annotation
RCA Reviewed computational analysis
Other:
IC Inferred by curator
NAS Non-traceable author statement
ND No biological data available
TAS Traceable author statement
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