Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables histone binding activity and transcription coactivator activity. Involved in several processes, including nucleosome assembly; positive regulation of transcription by RNA polymerase II; and protein localization to chromatin. Acts upstream of or within several processes, including apoptotic signaling pathway; negative regulation of DNA-templated transcription; and regulation of apoptotic process. Located in PML body and cytosol. Part of heterochromatin. Is expressed in several structures, including early embryo; genitourinary system; heart; hemolymphoid system gland; and liver. Human ortholog(s) of this gene implicated in appendiceal neoplasm; islet cell tumor; oral squamous cell carcinoma; ovary epithelial cancer; and pancreatic endocrine carcinoma. Orthologous to human DAXX (death domain associated protein).