Automated description from the Alliance of Genome Resources (Release 5.3.0)
Predicted to enable calcium ion binding activity and cell adhesion molecule binding activity. Predicted to be involved in several processes, including Purkinje myocyte development; homophilic cell adhesion via plasma membrane adhesion molecules; and regulation of heart contraction. Located in desmosome. Is expressed in several structures, including alimentary system; epithelium; genitourinary system; respiratory system; and vibrissa. Used to study arrhythmogenic right ventricular dysplasia 10. Human ortholog(s) of this gene implicated in arrhythmogenic right ventricular dysplasia 10 and dilated cardiomyopathy 1BB. Orthologous to human DSG2 (desmoglein 2).