Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including Notch signaling pathway; animal organ development; and negative regulation of transforming growth factor beta receptor signaling pathway. Localizes to nucleus. Is expressed in several structures, including central nervous system; gut; liver and biliary system; retina; and urinary system. Orthologous to human ONECUT1 (one cut homeobox 1).