Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources

Exhibits exonuclease activity. Involved in aging and mitochondrial DNA replication. Localizes to the mitochondrial inner membrane. Used to study bipolar disorder; mood disorder; and myelodysplastic syndrome. Human ortholog(s) of this gene implicated in several diseases, including mitochondrial DNA depletion syndrome (multiple); mitochondrial myopathy (multiple); neurodegenerative disease (multiple); ovarian disease (multiple); and sensory ataxic neuropathy, dysarthria, and ophthalmoparesis. Is expressed in several structures, including early conceptus and secondary oocyte. Orthologous to human POLG (DNA polymerase gamma, catalytic subunit).

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Gene Ontology Evidence Code Abbreviations:

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