Automated description from the Alliance of Genome Resources (Release 3.0)
Exhibits protein kinase binding activity. Involved in positive regulation of focal adhesion disassembly; positive regulation of keratinocyte migration; and regulation of postsynaptic neurotransmitter receptor internalization. Localizes to Schaffer collateral - CA1 synapse; glutamatergic synapse; and postsynaptic density, intracellular component. Is expressed in brain ventricular layer; sensory organ; telencephalon mantle layer; vestibulo-cochlear ganglion; and viscerocranium. Orthologous to human IQSEC1 (IQ motif and Sec7 domain ArfGEF 1).