Automated description from the Alliance of Genome Resources (Release 3.0)
Predicted to have tumor necrosis factor receptor binding activity. Involved in several processes, including animal organ development; cell-matrix adhesion; and positive regulation of signal transduction. Localizes to apical part of cell; endoplasmic reticulum membrane; and integral component of plasma membrane. Used to study hypohidrotic ectodermal dysplasia. Human ortholog(s) of this gene implicated in ectodermal dysplasia 1 and tooth agenesis. Is expressed in several structures, including alimentary system; brain; cornea epithelium; future brain; and skin. Orthologous to human EDA (ectodysplasin A).