Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables signaling receptor activity. Predicted to be involved in nervous system development; protein homotrimerization; and regulation of neuron apoptotic process. Predicted to act upstream of or within lipid transport. Located in postsynaptic density. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system gland; and liver. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 16 and autosomal recessive distal hereditary motor neuronopathy 2. Orthologous to human SIGMAR1 (sigma non-opioid intracellular receptor 1).