Automated description from the Alliance of Genome Resources
Exhibits signaling receptor activity. Involved in cell death in response to hydrogen peroxide. Localizes to the postsynaptic density. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 16 and autosomal recessive distal spinal muscular atrophy 2. Orthologous to human SIGMAR1 (sigma non-opioid intracellular receptor 1).