Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits signaling receptor activity. Involved in cell death in response to hydrogen peroxide. Localizes to postsynaptic density. Is expressed in several structures, including central nervous system; genitourinary system; hemolymphoid system gland; intraembryonic coelom; and liver. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 16 and distal spinal muscular atrophy 2. Orthologous to human SIGMAR1 (sigma non-opioid intracellular receptor 1).