Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits chromatin binding activity. Involved in several processes, including negative regulation of retinoic acid receptor signaling pathway; nervous system development; and nodal signaling pathway. Localizes to nucleus. Is expressed in several structures, including alimentary system; brain; early conceptus; embryo ectoderm; and genitourinary system. Used to study otitis media. Human ortholog(s) of this gene implicated in holoprosencephaly and holoprosencephaly 4. Orthologous to human TGIF1 (TGFB induced factor homeobox 1).