Automated description from the Alliance of Genome Resources (Release 5.2.0)
Enables several functions, including profilin binding activity; small GTPase binding activity; and transmembrane transporter binding activity. Involved in actin filament polymerization; brain development; and neuron projection development. Acts upstream of or within actin cytoskeleton organization. Located in several cellular components, including brush border; neuron projection; and ruffle membrane. Is expressed in several structures, including brain; genitourinary system; gut; liver; and lung. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 1 and sensorineural hearing loss. Orthologous to human DIAPH1 (diaphanous related formin 1).