Automated description from the Alliance of Genome Resources
Predicted to have endopeptidase activity; protein homodimerization activity; and zinc ion binding activity. Involved in pharyngeal system development. Predicted to localize to several cellular components, including the cytoplasmic vesicle; external side of plasma membrane; and perinuclear region of cytoplasm. Used to study double outlet right ventricle. Human ortholog(s) of this gene implicated in Alzheimer's disease; congestive heart failure; coronary artery disease; essential hypertension; and hypertension. Is expressed in several structures, including alimentary system; central nervous system; male reproductive gland or organ; respiratory system; and sensory organ. Orthologous to human ECE1 (endothelin converting enzyme 1).