Automated description from the Alliance of Genome Resources (Release 5.1.1)
Predicted to enable transforming growth factor beta binding activity. Acts upstream of or within several processes, including negative regulation of bone mineralization; negative regulation of chondrocyte differentiation; and positive regulation of bone resorption. Located in extracellular region. Is expressed in several structures, including cardiovascular system; jaw; limb; respiratory system; and ventricular layer. Used to study brachyolmia-amelogenesis imperfecta syndrome. Human ortholog(s) of this gene implicated in brachyolmia-amelogenesis imperfecta syndrome and geleophysic dysplasia 3. Orthologous to human LTBP3 (latent transforming growth factor beta binding protein 3).