Automated description from the Alliance of Genome Resources
Predicted to have transforming growth factor beta binding activity. Involved in several processes, including negative regulation of bone mineralization; negative regulation of chondrocyte differentiation; and positive regulation of bone resorption. Localizes to the extracellular region. Used to study brachyolmia-amelogenesis imperfecta syndrome. Human ortholog(s) of this gene implicated in brachyolmia-amelogenesis imperfecta syndrome. Is expressed in several structures, including cardiovascular system; jaw; limb; respiratory system; and ventricular layer. Orthologous to human LTBP3 (latent transforming growth factor beta binding protein 3).