Automated description from the Alliance of Genome Resources
Predicted to have several functions, including ATP-dependent microtubule motor activity, minus-end-directed; dynein intermediate chain binding activity; and dynein light chain binding activity. Involved in several processes, including cardiac septum morphogenesis; determination of left/right symmetry; and sperm flagellum movement involved in flagellated sperm motility. Localizes to the 9+0 motile cilium; 9+2 motile cilium; and proximal portion of axoneme. Used to study Kartagener syndrome; atrioventricular septal defect; primary ciliary dyskinesia 7; and visceral heterotaxy. Human ortholog(s) of this gene implicated in Kartagener syndrome and primary ciliary dyskinesia 7. Orthologous to human DNAH11 (dynein axonemal heavy chain 11).