Automated description from the Alliance of Genome Resources (Release 3.1.1)
Predicted to have ATP-dependent microtubule motor activity, minus-end-directed; dynein intermediate chain binding activity; and dynein light intermediate chain binding activity. Involved in several processes, including cardiac septum morphogenesis; determination of left/right symmetry; and flagellated sperm motility. Localizes to 9+0 motile cilium; 9+2 motile cilium; and proximal portion of axoneme. Is expressed in node. Used to study Kartagener syndrome; atrioventricular septal defect; primary ciliary dyskinesia 7; and visceral heterotaxy. Human ortholog(s) of this gene implicated in Kartagener syndrome and primary ciliary dyskinesia 7. Orthologous to human DNAH11 (dynein axonemal heavy chain 11).