Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables several functions, including nuclear receptor binding activity; promoter-specific chromatin binding activity; and transcription coregulator activity. Involved in several processes, including camera-type eye development; circulatory system development; and myeloid cell development. Acts upstream of or within several processes, including hemopoiesis; mammary gland development; and regulation of signal transduction. Located in nucleus. Part of mediator complex. Is expressed in several structures, including central nervous system; genitourinary system; gut; hemolymphoid system gland; and lung. Used to study congestive heart failure and dilated cardiomyopathy. Orthologous to human MED1 (mediator complex subunit 1).