Automated description from the Alliance of Genome Resources
Exhibits collagen binding activity. Involved in several processes, including circulatory system development; negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; and negative regulation of protein phosphorylation. Localizes to the nucleus and protein-containing complex. Predicted to colocalize with the catenin complex and cell-cell adherens junction. Human ortholog(s) of this gene implicated in pancreatic adenocarcinoma. Is expressed in several structures, including cardiovascular system; central nervous system; early conceptus; genitourinary system; and inner ear. Orthologous to human SMAD7 (SMAD family member 7).