Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including collagen fibril organization; nervous system development; and trabecular meshwork development. Localizes to nucleus. Is expressed in several structures, including central nervous system; hemolymphoid system; limb; respiratory system; and trunk mesenchyme. Used to study nail-patella syndrome. Human ortholog(s) of this gene implicated in nail-patella syndrome. Orthologous to human LMX1B (LIM homeobox transcription factor 1 beta).