Automated description from the Alliance of Genome Resources
Predicted to have protein kinase activity. Involved in chromosome segregation and positive regulation of intrinsic apoptotic signaling pathway. Localizes to the condensed nuclear chromosome, centromeric region and kinetochore. Human ortholog(s) of this gene implicated in colorectal cancer. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human BUB1 (BUB1 mitotic checkpoint serine/threonine kinase).