Automated description from the Alliance of Genome Resources (Release 7.0.0)
A structural constituent of presynaptic active zone. Involved in regulation of calcium-dependent activation of synaptic vesicle fusion; regulation of presynaptic cytosolic calcium ion concentration; and synaptic vesicle priming. Acts upstream of or within maintenance of presynaptic active zone structure. Located in synapse. Is active in GABA-ergic synapse; glutamatergic synapse; and presynaptic active zone cytoplasmic component. Is expressed in several structures, including central nervous system; gut; peripheral nervous system ganglion; sensory organ; and urinary system. Orthologous to human ERC2 (ELKS/RAB6-interacting/CAST family member 2).