Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables folic acid:proton symporter activity; heme transmembrane transporter activity; and methotrexate transmembrane transporter activity. Involved in folate import across plasma membrane and heme transport. Located in apical plasma membrane and cytoplasm. Is active in basolateral plasma membrane. Is expressed in adrenal gland; early conceptus; gonad; metanephros; and spinal cord. Human ortholog(s) of this gene implicated in hereditary folate malabsorption. Orthologous to human SLC46A1 (solute carrier family 46 member 1).