Automated description from the Alliance of Genome Resources
Exhibits several functions, including disordered domain specific binding activity; protein heterodimerization activity; and transcription factor binding activity. Predicted to contribute to DNA-binding transcription factor activity. Involved in several processes, including cellular response to hepatocyte growth factor stimulus; face morphogenesis; and regulation of macromolecule biosynthetic process. Localizes to the condensed chromosome outer kinetochore and nucleus. Used to study Rubinstein-Taybi syndrome; acute myeloid leukemia; autism spectrum disorder; and myelodysplastic syndrome. Human ortholog(s) of this gene implicated in Rubinstein-Taybi syndrome; acute myeloid leukemia; and precursor lymphoblastic lymphoma/leukemia. Is expressed in several structures, including central nervous system; genitourinary system; heart; liver; and lung epithelium. Orthologous to human CREBBP (CREB binding protein).