Automated description from the Alliance of Genome Resources
Exhibits kinetochore binding activity and protein kinase binding activity. Involved in several processes, including attachment of spindle microtubules to kinetochore; positive regulation of attachment of spindle microtubules to kinetochore; and regulation of mitotic metaphase/anaphase transition. Localizes to the condensed chromosome outer kinetochore and condensed nuclear chromosome kinetochore. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 13. Orthologous to human CENPE (centromere protein E).