Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable cysteine-type endopeptidase inhibitor activity; hormone activity; and protease binding activity. Predicted to be involved in several processes, including antimicrobial humoral immune response mediated by antimicrobial peptide; negative regulation of blood coagulation; and vasodilation. Predicted to act upstream of or within blood coagulation; blood vessel diameter maintenance; and inflammatory response. Located in collagen-containing extracellular matrix. Is expressed in yolk sac. Human ortholog(s) of this gene implicated in hereditary angioedema and high molecular weight kininogen deficiency. Orthologous to human KNG1 (kininogen 1).