Automated description from the Alliance of Genome Resources
Exhibits 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity and microtubule binding activity. Involved in base-excision repair. Localizes to the mitochondrion and nucleus. Human ortholog(s) of this gene implicated in several diseases, including Graves' disease; angiomyolipoma; carcinoma (multiple); endocrine gland cancer (multiple); and eye disease (multiple). Orthologous to human OGG1 (8-oxoguanine DNA glycosylase).