Automated description from the Alliance of Genome Resources (Release 3.0)
Exhibits Wnt-protein binding activity; protein homodimerization activity; and protein tyrosine phosphatase activity. Involved in several processes, including lamellipodium assembly; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity; and slit diaphragm assembly. Localizes to several cellular components, including GABA-ergic synapse; integral component of postsynaptic density membrane; and lateral plasma membrane. Human ortholog(s) of this gene implicated in nephrotic syndrome type 6. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and spinal cord. Orthologous to human PTPRO (protein tyrosine phosphatase receptor type O).