Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables Wnt-protein binding activity; protein homodimerization activity; and protein tyrosine phosphatase activity. Involved in several processes, including plasma membrane bounded cell projection organization; podocyte differentiation; and slit diaphragm assembly. Located in apical plasma membrane; dendritic spine; and lateral plasma membrane. Is active in GABA-ergic synapse; glutamatergic synapse; and postsynaptic density membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and spinal cord. Human ortholog(s) of this gene implicated in nephrotic syndrome type 6. Orthologous to human PTPRO (protein tyrosine phosphatase receptor type O).