Automated description from the Alliance of Genome Resources
Predicted to have Notch binding activity. Involved in several processes, including anterior/posterior pattern specification; negative regulation of neurogenesis; and paraxial mesoderm development. Predicted to localize to the plasma membrane. Used to study spondylocostal dysostosis. Human ortholog(s) of this gene implicated in dysostosis and spondylocostal dysostosis. Is expressed in several structures, including blastocyst; central nervous system; future brain; paraxial mesenchyme; and sensory organ. Orthologous to human DLL3 (delta like canonical Notch ligand 3).