Automated description from the Alliance of Genome Resources
Predicted to contribute to RNA polymerase I activity. Predicted to be involved in negative regulation of protein localization to nucleolus and rRNA transcription. Localizes to the RNA polymerase I complex. Human ortholog(s) of this gene implicated in acrofacial dysostosis Cincinnati type. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and limb. Orthologous to human POLR1A (RNA polymerase I subunit A).